Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells
Stefan Semrau, Johanna Goldmann, Magali Soumillon, Tarjei S. Mikkelsen, Rudolf Jaenisch, Alexander van Oudenaarden
This study uses single-cell transcriptomics to analyze lineage commitment in differentiating mouse embryonic stem cells, identifying key transcriptional changes and a phase of susceptibility to lineage signals.
bioRxiv · Aug 7, 2016Systems Biology