Author

Christopher B Burge

Primary ORCID profile (0000-0001-9047-5648 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Christopher B BurgeiD1 paper · MIT

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Edoardo M Airoldi· 2 shared Yarden Katz· 2 shared Albert W Cheng· 1 shared Anne Dumaine· 1 shared Ariane Page Sabourin· 1 shared Athma A Pai· 1 shared Bang Wong· 1 shared Christopher J Lengner· 1 shared

Activity by Year

2014-2016 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersGenomics

Edoardo M Airoldi

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3 papers

Recent·Most cited

Widespread shortening of 3’ untranslated regions and increased exon inclusion are evolutionarily conserved features of innate immune responses to infection

Athma A Pai, Golshid Baharian, Ariane Page Sabourin, Jessica F Brinkworth, Yohann Nedelec, Joseph W Foley, Jean-Christophe Grenier, Katherine J Siddle, Anne Dumaine, Vania Yotova, Zachary P Johnson, Robert E Lanford, Christopher B Burge, Luis B Barreiro

The paper identifies widespread changes in RNA processing, including shorter 3’ UTRs and increased exon inclusion, in innate immune responses across humans and non-human primates.

PLOS Genetics · Sep 30, 2016Peer-reviewedGenomics

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

Yarden Katz, Feifei Li, Nicole Lambert, Ethan M Sokol, Wai-Leong Tam, Albert W Cheng, Edoardo M Airoldi, Christopher J Lengner, Piyush B Gupta, Zhengquan Yu, Rudolf Jaenisch, Christopher B Burge

This study identifies Musashi proteins as regulators of the epithelial-luminal cell state by repressing EMT and promoting epithelial gene expression in neural and breast cells.

bioRxiv · Jun 12, 2014Genomics

Sashimi plots: Quantitative visualization of alternative isoform expression from RNA-seq data

Yarden Katz, Eric T Wang, Jacob Stilterra, Schraga Schwartz, Bang Wong, Helga Thorvaldsdóttir, James T Robinson, Jill P Mesirov, Edoardo M Airoldi, Christopher B Burge

The paper introduces Sashimi plots as a method to visualize and compare isoform expression across multiple RNA-Seq samples.

bioRxiv · Feb 11, 2014Bioinformatics