Author

Rui Cao

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genetic & Genomic Medicine· 2 Developmental Biology· 1 Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Logan G. SpectoriD· 2 shared Tianzhong YangiD· 2 shared Andrew R. RaduskiiD· 1 shared Binghong CheniD· 1 shared Chen ZhangiD· 1 shared Chunlin LiiD· 1 shared Cindy ImiD· 1 shared Dong WangiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Logan G. SpectorORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Pseudotime-Dependent TWAS Framework Identifies Disease Genes along Cell Developmental Paths

Rui Cao, Chunlin Li, Erjia Cui, Logan G. Spector, Andrew R. Raduski, Nathan Anderson, Weihua Guan, Peter Gordon, Cindy Im, Tianzhong Yang

The paper introduces pt-TWAS, a framework that identifies disease genes along cell developmental paths by modeling gene expression as a continuous function of pseudotime, improving resolution over discrete cell-type analyses.

Human Genetics and Genomics Advances · Jun 23, 2026Peer-reviewedGenetic & Genomic Medicine

Unsilenced inhibitory cortical ensemble gates remote memory retrieval

Shaoli Wang, Tao Sheng, Feng Su, Yang He, Rui Cao, Qiao Wang, Weiqun Fang, Chen Zhang, Wei Lu

The paper identifies a subset of GABAergic neurons in the ACC that gate remote memory retrieval through persistent activity and synchronization.

Cell Reports · Sep 27, 2025Peer-reviewedNeuroscience

Rhamnose-mediated modulation of hair follicle growth: insights from chemical genomics

Xiu Li, Ying Liu, Lu Li, Wenjie Jiang, Shize Ma, Rui Cao, Yi Zhang, Ran Xiao, Dong Wang, Zhigang Yang

This study identifies rhamnose as a compound that promotes hair follicle growth by restoring hair-inducing gene expression and inducing glucose metabolism remodeling.

bioRxiv · Jan 26, 2025 · PreprintPharmacology & Toxicology

Subset scanning for multi-trait analysis using GWAS summary statistics

Rui Cao, EVAN A. OLAWSKY, Edward McFowland, Erin L. Marcotte, Logan G. Spector, Tianzhong Yang

TraitScan identifies relevant subsets of traits from large genetic datasets, improving multi-trait analysis power and outperforming existing methods in simulations and real-world application to Ewing Sarcoma.

Bioinformatics · Jan 1, 2024Peer-reviewedGenetic & Genomic Medicine

Melatonin alleviates valproic acid-induced neural tube defects by modulating Src/PI3K/ERK signaling and oxidative stress

Yuxiang Liang, Ying Wang, Xiao Zhang, Shanshan Jin, Yuqian Guo, Zhaowei Yu, Xinrui Xu, Qizhi Shuai, Zihan Feng, Binghong Chen, Ting Liang, Ruifang Ao, Jianting Li, Juan Zhang, Rui Cao, , Jun Xie

Acta Biochimica et Biophysica Sinica · Sep 13, 2023Peer-reviewedDevelopmental Biology