Ruiling Zhong

Analysis in vivo using a new method, ARGO (Analysis of Red Green Offset), reveals complexity and cell-type specificity in presynaptic turnover of synaptic vesicle protein Synaptogyrin/SNG-1

This paper introduces ARGO, a method to quantify protein turnover in vivo, and uses it to show that Synaptogyrin/SNG-1 partitions into two distinct presynaptic pools with different turnover rates in C. elegans neurons.

TFEB/HLH-30-mediated expansion of neuronal lysosomal capacity in early adulthood protects dendrite maintenance during aging in Caenorhabditis elegans

This study shows that HLH-30/TFEB expands neuronal lysosomal capacity in early adulthood, protecting dendrite maintenance during aging in C. elegans.