Author

Ruxin Lei

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Youwen ZhuangiD· 2 shared H. Eric XuiD· 1 shared Heng LiuiD· 1 shared Jian ZhangiD· 1 shared Jianhui Zhou· 1 shared Jingjing HouiD· 1 shared Jun Sun· 1 shared Luyu FaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Youwen ZhuangORCID

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2 papers

Recent·Most cited

Multi-vector retrieval enables residue-resolved prediction of protein partners by ColBERT-PPI

Yang He, Ruxin Lei, Youwen Zhuang, Jian Zhang

ColBERT-PPI predicts protein partners and their binding sites at the residue level using a multi-vector framework, outperforming existing methods on benchmark datasets.

bioRxiv · Sep 24, 2026 · PreprintBioinformatics

Molecular principles for graded activation of dopamine D1 receptor

Xinyue Zhang, Yu Zheng, Heng Liu, Jingjing Hou, Luyu Fan, Xinheng He, Jun Sun, Tao Liu, Jianhui Zhou, Ruxin Lei, Mingyang Li, Wen Hu, Xi Cheng, Sheng Wang, Xin Xie, , Youwen Zhuang

The paper defines the molecular mechanism of graded activation of the dopamine D1 receptor and shows how ligand efficacy is encoded through an activation pathway.

bioRxiv · Jul 29, 2026 · PreprintBiochemistry