Author

Ryan Kelly

National Institutes of HealthPrimary ORCID profile (0000-0002-3339-4443 · 11 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Ryan KellyiD11 papers · Brigham Young University

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anna GaultoniD· 1 shared Anneli Karlsson· 1 shared Aroon Hingorani· 1 shared Chris FinaniD· 1 shared Felix Kruger· 1 shared Francisco Pereira LoboiD· 1 shared Haley Tran· 1 shared John Overington· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetics

Anna GaultonORCID

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2 papers

Recent·Most cited

Sp Transcription Factors Establish the Signaling Environment in the Neuromesodermal Progenitor Niche During Axial Elongation

Ravindra B. Chalamalasetty, Haley Tran, Ryan Kelly, Samuel Kuo, Mark W. L. Kennedy, Moonsup Lee, Sara Thomas, Nikolaos Panagiotis Mandalos, Vishal N. Kopardé, Francisco Pereira Lobo, Terry P. Yamaguchi

The paper identifies Sp5/8 as essential regulators of neuromesodermal progenitor maintenance through their role in sustaining Wnt/Fgf signaling and repressing retinoic acid activity.

bioRxiv · Jun 3, 2025 · PreprintDevelopmental Biology

The druggable genome and support for target identification and validation in drug development

Chris Finan, Anna Gaulton, Felix Kruger, Tom Lumbers, Tina Shah, Jorgen Engmann, Luana Galver, Ryan Kelly, Anneli Karlsson, Rita Santos, John Overington, Aroon Hingorani, Juan Pablo Casas

The paper connects GWAS loci to druggable genes, compounds, and clinical indications to identify drug development opportunities and design a genotyping array for druggable genome-wide association studies.

Science Translational Medicine · Mar 29, 2017Peer-reviewedGenetics