Author

Moonsup Lee

National Institutes of HealthORCID 0000-0002-7452-2018Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Francisco Pereira LoboiD· 2 shared Mark W. L. KennedyiD· 2 shared Ravindra B. ChalamalasettyiD· 2 shared Terry P. YamaguchiiD· 2 shared Alexandra L. JoyneriD· 1 shared Anna‐Katerina HadjantonakisiD· 1 shared Daniel N. StepheniD· 1 shared Haley Tran· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersDevelopmental Biology

Francisco Pereira LoboORCID

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2 papers

Recent·Most cited

Transcription factors SP5 and SP8 drive primary cilia formation

Yinwen Liang, Richard P. Koche, Ravindra B. Chalamalasetty, Daniel N. Stephen, Mark W. L. Kennedy, Zhimin Lao, Yunong Pang, Ying-Yi Kuo, Moonsup Lee, Francisco Pereira Lobo, Xiaofeng Huang, Anna‐Katerina Hadjantonakis, Terry P. Yamaguchi, Kathryn V. Anderson, Alexandra L. Joyner

This study identifies SP5 and SP8 as transcription factors that drive primary cilia formation through genetic and transcriptomic analyses in mouse embryos.

Science · Aug 28, 2025Peer-reviewedDevelopmental Biology

Sp Transcription Factors Establish the Signaling Environment in the Neuromesodermal Progenitor Niche During Axial Elongation

Ravindra B. Chalamalasetty, Haley Tran, Ryan Kelly, Samuel Kuo, Mark W. L. Kennedy, Moonsup Lee, Sara Thomas, Nikolaos Panagiotis Mandalos, Vishal N. Kopardé, Francisco Pereira Lobo, Terry P. Yamaguchi

The paper identifies Sp5/8 as essential regulators of neuromesodermal progenitor maintenance through their role in sustaining Wnt/Fgf signaling and repressing retinoic acid activity.

bioRxiv · Jun 3, 2025 · PreprintDevelopmental Biology