Author

S. Abbondante

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

E. Pearlman· 2 shared A. P. Huang· 1 shared A. Rietsch· 1 shared A. Siryaporn· 1 shared B. A. Miller· 1 shared G. Dubyak· 1 shared I. P. Foik· 1 shared J. Tran-Chau· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

E. Pearlman

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The NLRP3 inflammasome selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates bacterial killing in vivo

M. Minns, T. Lima, K. Liboro, S. Abbondante, B. A. Miller, M. Marshall, J. Tran-Chau, A. Rietsch, G. Dubyak, E. Pearlman

This study shows that Pseudomonas aeruginosa uses ExoS to redirect neutrophil inflammasome signaling from NLRC4 to NLRP3, enhancing bacterial killing and reducing disease severity in mice.

bioRxiv · Apr 7, 2022 · PreprintMicrobiology

Bacteria detect neutrophils via a system that responds to hypochlorous acid and flow

I. P. Foik, S. J. Kasallis, R. Shu, S. Abbondante, M. E. Marshall, L. A. Urban, L. Duong, A. P. Huang, E. Pearlman, T. L. Downing, A. Siryaporn

This study shows Pseudomonas aeruginosa detects neutrophil-derived hypochlorous acid and uses it to upregulate the Fro operon, enhancing survival during infection.

bioRxiv · Feb 1, 2022 · PreprintMicrobiology