Author

S. Alonso-Gil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:structural biology· 2 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Stadler· 2 shared B. Zagrovic· 2 shared G. Dong· 2 shared J. Sunter· 2 shared S. Vaughan· 2 shared B. Villarejo-Zori· 1 shared E. Sierra-Filardi· 1 shared G. Marino· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

A. Stadler

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Author profile →

3 papers

Recent·Most cited

The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body

A. Stadler, S. Alonso-Gil, B. Zagrovic, S. Vaughan, J. Sunter, G. Dong

This study determines the structure of CFAP410's C-terminal domain and shows that its tetrameric helical bundle is essential for basal body localization, explaining how the L224P mutation causes ciliopathies.

bioRxiv · Nov 30, 2023Biochemistry

CFAP410 has a bimodular architecture with a conserved surface patch on its N-terminal LRR motif for binding interaction partners

A. Stadler, H. B. Gabriel, L. V. De Liz, S. Alonso-Gil, X. Deng, R. Crickley, K. Korbula, K. Huang, B. Zagrovic, S. Vaughan, J. Sunter, G. Dong

This study reports the crystal structure of the N-terminal domain of CFAP410 and shows how mutations in this domain disrupt its structural stability and interaction with partners, leading to disease.

bioRxiv · Sep 21, 2022 · PreprintBiochemistry

Ambra1 haploinsufficiency results in metabolic alterations and exacerbates age-associated retinal degeneration

I. Ramirez-Pardo, B. Villarejo-Zori, J. I. Jimenez-Loygorri, E. Sierra-Filardi, S. Alonso-Gil, G. Marino, P. de la Villa, P. S. Fitze, J. M. Fuentes, R. Garcia-Escudero, R. Gomez-Sintes, P. Boya

This study shows that reduced Ambra1 levels in mice lead to metabolic issues and faster retinal degeneration, suggesting autophagy's role in protecting against aging-related vision loss.

bioRxiv · Feb 4, 2022 · PreprintCell Biology