The Defenders of the Alveolus Succumb in COVID-19 Pneumonia to SARS-CoV-2, Necroptosis, Pyroptosis and Panoptosis
L. Schifanella, J. Anderson, G. Wieking, P. J. Southern, S. Antinori, M. Galli, M. Corbellino, A. Lai, N. Klatt, T. Schacker, A. T. Haase
This paper investigates how SARS-CoV-2 infection leads to the destruction of alveolar type II cells in fatal COVID-19 pneumonia through multiple inflammatory cell death pathways and suggests potential therapeutic strategies.
bioRxiv · Aug 6, 2022Immunology