Impact of Human Serum Proteins on Susceptibility of Acinetobacter baumannii to Cefiderocol: role of iron transport
C. Le, C. Pimentel, F. Pasteran, M. R. Tuttobene, T. Subils, J. Escalante, B. Nishimura, S. Arriaga, A. Carranza, A. J. Vila, A. Corso, L. A. Actis, M. Tolmasky, R. A. Bonomo, M. S. Ramirez
The paper shows that human serum and its components increase Acinetobacter baumannii resistance to cefiderocol by altering iron uptake and beta-lactam resistance genes.
bioRxiv · Aug 18, 2021Microbiology