Author

M. R. Tuttobene

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. S. Ramirez· 4 shared M. Tolmasky· 4 shared R. A. Bonomo· 4 shared B. Nishimura· 3 shared T. Subils· 3 shared A. Corso· 2 shared C. Le· 2 shared C. Pimentel· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

M. S. Ramirez

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp.

O. Wong, V. Mezcord, C. Lopez, G. M. Traglia, F. Pasteran, M. R. Tuttobene, A. Corso, M. Tolmasky, R. A. Bonomo, M. S. Ramirez

This study investigates the molecular mechanisms of cefiderocol resistance and antagonism with avibactam and sulbactam in carbapenem-resistant Acinetobacter strains.

bioRxiv · Mar 4, 2024 · PreprintMicrobiology

The Iron Content of Human Serum Albumin Modulates the Susceptibility of Acinetobacter baumannii to Cefiderocol

J. Escalante, B. Nishimura, M. R. Tuttobene, T. Subils, V. Mezcord, L. A. Actis, M. Tolmasky, R. A. Bonomo, M. S. Ramirez

This paper shows that human serum albumin (HSA) increases Acinetobacter baumannii resistance to cefiderocol by modulating iron uptake and beta-lactam resistance gene expression.

bioRxiv · Aug 24, 2022Microbiology

Impact of Human Serum Proteins on Susceptibility of Acinetobacter baumannii to Cefiderocol: role of iron transport

C. Le, C. Pimentel, F. Pasteran, M. R. Tuttobene, T. Subils, J. Escalante, B. Nishimura, S. Arriaga, A. Carranza, A. J. Vila, A. Corso, L. A. Actis, M. Tolmasky, R. A. Bonomo, M. S. Ramirez

The paper shows that human serum and its components increase Acinetobacter baumannii resistance to cefiderocol by altering iron uptake and beta-lactam resistance genes.

bioRxiv · Aug 18, 2021Microbiology

Interplay between meropenem and human serum albumin on expression of carbapenem resistance genes and natural competence in Acinetobacter baumannii

C. Pimentel, C. Le, M. R. Tuttobene, T. Subils, B. Nishimura, G. M. Traglia, F. Perez, K. M. Papp-Wallace, R. A. Bonomo, M. Tolmasky, M. S. Ramirez

This study shows that human serum albumin and meropenem together enhance natural transformation and gene expression in Acinetobacter baumannii, potentially promoting resistance and evolution.

bioRxiv · May 14, 2021Microbiology