De novo emergence of adaptive membrane proteins from thymine-rich intergenic sequences
N. Vakirlis, O. Acar, B. Hsu, N. Castilho Coelho, S. B. Van Oss, A. Wacholder, K. Medetgul-Ernar, J. Ianotta, A. McLysaght, C. J. Camacho, A. F. O'Donnell, T. Ideker, A.-R. Carvunis
This study shows that de novo emerging coding sequences in yeast often encode beneficial transmembrane proteins, suggesting that intergenic regions may contain pre-existing blueprints for such functions.
bioRxiv · Apr 29, 2019Evolutionary Biology