Author

S. Belkaya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. F. Stenzel· 1 shared A. W. Ashbrook· 1 shared B. A. Ersoy· 1 shared B. Razooky· 1 shared B. Zeck· 1 shared C. G. Fulmer· 1 shared C. M. Rice· 1 shared C. Quirk· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPathology

A. F. Stenzel

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2 papers

Recent·Most cited

Rational Design of Monomeric IL37 Variants Guided by Stability and Dynamical Analyses of IL37 Dimers

I. Sardag, Z. S. Duvenci, S. Belkaya, E. Timucin

This paper identifies five IL37 mutations that disrupt dimer formation while preserving monomer structure, aiding in the design of anti-inflammatory therapeutics.

bioRxiv · Feb 6, 2024Immunology

Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice

M. Kabbani, E. Michailidis, S. Steensels, C. G. Fulmer, J. M. Luna, J. Le Pen, M. Tardelli, B. Razooky, I. Ricardo-Lax, C. Zou, B. Zeck, A. F. Stenzel, C. Quirk, L. Foquet, A. W. Ashbrook, , Y. P. de Jong

This study shows that the PNPLA3 148M variant in human hepatocytes worsens non-alcoholic steatohepatitis in chimeric mice on a hypercaloric diet.

bioRxiv · Nov 19, 2020 · PreprintPathology