Author

C. Quirk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

C. M. Rice· 4 shared C. Zou· 3 shared E. Michailidis· 3 shared M. Kabbani· 3 shared W. M. Schneider· 3 shared Y. P. de Jong· 3 shared A. W. Ashbrook· 2 shared C. Jahan· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersImmunology

C. M. Rice

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection.

A. Lercher, J.-G. Cheong, C. Jiang, H.-H. Hoffmann, A. W. Ashbrook, Y. S. Yin, C. Quirk, E. J. DeGrace, L. Chiriboga, B. R. Rosenberg, S. Z. Josefowicz, C. M. Rice

This study shows that SARS-CoV-2 infection primes alveolar macrophages for enhanced antiviral responses against influenza A virus through epigenetic changes in IFN-I pathways.

bioRxiv · Nov 24, 2023 · PreprintImmunology

Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice

M. Kabbani, E. Michailidis, S. Steensels, C. G. Fulmer, J. M. Luna, J. Le Pen, M. Tardelli, B. Razooky, I. Ricardo-Lax, C. Zou, B. Zeck, A. F. Stenzel, C. Quirk, L. Foquet, A. W. Ashbrook, , Y. P. de Jong

This study shows that the PNPLA3 148M variant in human hepatocytes worsens non-alcoholic steatohepatitis in chimeric mice on a hypercaloric diet.

bioRxiv · Nov 19, 2020 · PreprintPathology

Public broadly neutralizing antibodies against hepatitis B virus in individuals with elite serologic activity

Q. Wang, E. Michailidis, Y. Yu, Z. Wang, A. M. Hurley, D. A. Oren, C. T. Mayer, A. Gazumyan, Z. Liu, Y. Zhou, T. Schoofs, K.-h. Yao, J. Nieke, J. Wu, Q. Jiang, , M. C. Nussenzweig

The paper identifies broadly neutralizing antibodies against HBV in elite neutralizers and shows that combinations of bNAbs targeting different epitopes are more effective than single bNAbs.

bioRxiv · Mar 4, 2020 · PreprintImmunology

An RNA-based system to study hepatitis B virus replication and select drug-resistance mutations

Y. Yu, W. M. Schneider, E. Michailidis, A. Acevedo, Y. Ni, P. Ambrose, C. Zou, M. Kabbani, C. Quirk, C. Jahan, X. Wu, S. Urban, A. Shlomai, Y. P. de Jong, C. M. Rice

This paper describes an RNA-based system to study HBV replication and predict drug resistance mutations.

bioRxiv · Oct 2, 2019 · PreprintMicrobiology