S. Blaess

A missense mutation (C667F) in beta-dystroglycan results in reduced dystroglycan protein levels leading to myopathy and destabilization of the blood-brain and blood-retinal barrier protein network

This study creates a mouse model of a beta-dystroglycan mutation causing myopathy and altered blood-brain and blood-retinal barrier protein networks, but not severe developmental issues seen in humans.

Two birds with one stone: human SIRPα nanobodies for functional modulation and in vivo imaging of myeloid cells

This study develops human SIRPα nanobodies for both functional modulation of myeloid cells and in vivo imaging of tumor infiltration.