Author

D. I. Frecot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:fluorescence / live-cell microscopy· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

P. D. Kaiser· 4 shared U. Rothbauer· 4 shared T. R. Wagner· 3 shared B. Traenkle· 2 shared S. Nueske· 2 shared A. J. Garcia-Saez· 1 shared A. Jenner· 1 shared A. M. Scholz· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersBiochemistry

P. D. Kaiser

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1

T. Froehlich, A. Jenner, C. Cavarischia-Rega, F. O. Fagbadebo, Y. Lurz, D. I. Frecot, P. D. Kaiser, S. Nueske, A. Scholz, E. Schaeffer, A. J. Garcia-Saez, B. Macek, U. Rothbauer

This study develops nanobodies to monitor Drp1, a mitochondrial fission factor, using proteomics, microscopy, and live-cell imaging techniques to study its dynamics in disease models.

bioRxiv · Dec 18, 2023 · PreprintCell Biology

Two birds with one stone: human SIRPα nanobodies for functional modulation and in vivo imaging of myeloid cells

T. R. Wagner, S. Blaess, I. Leske, D. I. Frecot, M. Gramlich, B. Traenkle, P. D. Kaiser, D. Seyfried, S. Maier, A. Rezza, F. Sonego, K. Thiam, S. Pezzana, A. Zeck, C. Gouttefangeas, , U. Rothbauer

This study develops human SIRPα nanobodies for both functional modulation of myeloid cells and in vivo imaging of tumor infiltration.

bioRxiv · Jun 27, 2023Immunology

Monitoring extracellular ion and metabolite dynamics with recombinant nanobody-fused biosensors

S. Burgstaller, T. R. Wagner, H. Bischof, S. Bueckle, A. Padamsey, D. I. Frecot, P. D. Kaiser, D. Skrabak, R. Malli, R. Lukowski, U. Rothbauer

This study develops recombinant nanobody-fused biosensors to monitor extracellular K+, pH, and glucose in real time, demonstrating their utility in cancer and neuronal cells.

bioRxiv · Apr 12, 2022Biochemistry

A broadly neutralizing biparatopic Nanobody protects mice from lethal challenge with SARS-CoV-2 variants of concern

T. R. Wagner, D. Schnepf, J. Beer, K. Klingel, N. Ruetalo, P. D. Kaiser, D. Junker, M. Sauter, B. Traenkle, D. I. Frecot, M. Becker, N. Schneiderhan-Marra, A. Ohnemus, M. Schwemmle, M. Schindler, U. Rothbauer

This study identifies a biparatopic nanobody that protects mice from lethal SARS-CoV-2 infection and reduces viral load and inflammation.

bioRxiv · Aug 8, 2021 · PreprintBiochemistry