Light-inducible T cell engagers trigger, tune and shape the activation of primary T cells
M. Jaeger, A. Anastasio, S. Brustlein, R. Vincentelli, F. Durbesson, R. Char, M. Boussand, M. Lechelon, R. J. Arguello, D. Marguet, H.-T. He, R. Lasserre
The paper introduces a light-inducible T cell engager system to study how temporal TCR stimulation patterns influence T cell activation and cytokine responses.
bioRxiv · Apr 15, 2022 · PreprintImmunology