Cell BiologyFrontiers in Chemical BiologyPeer-reviewed
Development of SYK NanoBRET Cellular Target Engagement Assays for Gain-of-Function Variants
Jacob L. Capener, James D. Vasta, Vittorio L. Katis…·Frances M. Bashore
The paper develops a NanoBRET assay to study SYK gain-of-function variants in live cells and demonstrates inhibitor efficacy against these variants.
6 citations