Inflammation Of The Retinal Pigment Epithelium Drives Early-Onset Photoreceptor Degeneration In Mertk-Associated Retinitis Pigmentosa
M. E. Mercau, Y. T. Akalu, F. Mazzoni, G. Gyimesi, E. J. Alberto, Y. Kong, B. Hafler, S. C. Finnemann, C. V. Rothlin, S. Ghosh
This study shows that RPE inflammation, not failed phagocytosis, drives early-onset photoreceptor degeneration in Mertk-deficient mice.
bioRxiv · Oct 8, 2022Immunology