The LUBAC participates in Lysophosphatidic Acid-induced NF-κB Activation
T. Douanne, S. Chapelier, R. Rottapel, J. Gavard, N. Bidere
This study shows that LUBAC is essential for LPA-induced NF-κB activation through MALT1-mediated cleavage of HOIL1 and GEF-H1-dependent regulation.
bioRxiv · Feb 13, 2020Immunology