CELF1 is an EIF4E binding protein that promotes translation of epithelial-mesenchymal transition effector mRNAs
A. Chaudhury, R. Pal, N. Kongchan, N. Zhao, Y. Zhu, E. Olokpa, S. Cheema, S. del Rincon, L. C. Reineke, S. Mao, R. E. Llyod, M. Sardiello, J. M. Rosen, J. R. Neilson
The paper shows CELF1 binds eIF4E and PABP to promote translation of EMT effector mRNAs, and disrupting this interaction inhibits EMT and metastasis.
bioRxiv · May 16, 2019 · PreprintCancer Biology