Author

S. E. Le Devedec

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

J. L. Stevens· 2 shared A. Gabor· 1 shared B. v. d. Water· 1 shared B. v. de Water· 1 shared C. Fisher· 1 shared C. Pont· 1 shared D. Clausznitzer· 1 shared E. Vaughan· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. L. Stevens

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2 papers

Recent·Most cited

A Network-based Transcriptomic Landscape of HepG2 cells to Uncover Causal Gene Cytotoxicity Interactions Underlying Drug-Induced Liver Injury

L. Wijaya, A. Gabor, I. Pot, L. v. der Have, J. Saez-Rodriguez, J. L. Stevens, S. E. Le Devedec, G. Callegaro, B. v. de Water

This study uses network-based transcriptomic analysis of HepG2 cells exposed to DILI compounds to identify causally linked genes involved in drug-induced liver injury.

bioRxiv · Jan 16, 2023 · PreprintPharmacology & Toxicology

Spatio-temporal transcriptomic analysis reveals distinct nephrotoxicity, DNA damage and regeneration response after cisplatin

L. S. Wijaya, S. Kunnen, P. Trairatphisan, C. Fisher, M. Crosby, K. Schaefer, K. Bodie, E. Vaughan, L. Breidenbach, T. Reich, D. Clausznitzer, S. A. Bonnet, S. Zheng, C. Pont, J. L. Stevens, , B. v. d. Water

This study uses spatial transcriptomics to analyze cisplatin-induced nephrotoxicity and regeneration in different kidney segments, identifying distinct molecular responses and biomarkers.

bioRxiv · Jan 3, 2023Pharmacology & Toxicology