Author

S. E. Murthy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Assay:electrophysiology· 1 Approach:mechanistic / dynamical model· 1 Organism:plant (other)· 1 Research Focus:protein structure prediction· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

A. B. Ward· 2 shared A. Patapoutian· 2 shared C. C. Tsui· 2 shared K. Saotome· 2 shared M. S. P. Sansom· 2 shared S. Jojoa Cruz· 1 shared S. Jojoa-Cruz· 1 shared W.-H. Lee· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 26 mutual co-author links

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2 shared papersBiochemistry

A. B. Ward

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2 papers

Recent·Most cited

Structural Insights into the Venus flytrap Mechanosensitive Ion Channel Flycatcher1

S. Jojoa-Cruz, K. Saotome, C. C. Tsui, W.-H. Lee, M. S. P. Sansom, S. E. Murthy, A. Patapoutian, A. B. Ward

This study characterizes the mechanosensitive ion channel FLYC1 using cryo-EM, MD simulations, and electrophysiology, revealing structural features and conformational transitions involved in mechano-gating.

bioRxiv · Jun 30, 2021Biochemistry

Cryo-EM structure of the mechanically activated ion channel OSCA1.2

S. Jojoa Cruz, K. Saotome, S. E. Murthy, C. C. Tsui, M. S. P. Sansom, A. Patapoutian, A. B. Ward

The paper presents the cryo-EM structure of the mechanically activated ion channel OSCA1.2 and supports its role in mechanosensation.

bioRxiv · Sep 4, 2018Biophysics