Author

S. Jojoa-Cruz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Approach:experimental assay· 2 Organism:Arabidopsis· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:mechanistic / dynamical model· 1 Organism:plant (other)· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

A. B. Ward· 2 shared W.-H. Lee· 2 shared A. E. Dubin· 1 shared A. Patapoutian· 1 shared C. C. Tsui· 1 shared K. Saotome· 1 shared M. S. P. Sansom· 1 shared S. E. Murthy· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

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2 shared papersBiochemistry

A. B. Ward

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2 papers

Recent·Most cited

Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli

S. Jojoa-Cruz, A. E. Dubin, W.-H. Lee, A. B. Ward

The paper identifies structural elements in OSCA channels that differentially mediate stretch and poking activation through mutagenesis and electrophysiology.

bioRxiv · Oct 3, 2023Biochemistry

Structural Insights into the Venus flytrap Mechanosensitive Ion Channel Flycatcher1

S. Jojoa-Cruz, K. Saotome, C. C. Tsui, W.-H. Lee, M. S. P. Sansom, S. E. Murthy, A. Patapoutian, A. B. Ward

This study characterizes the mechanosensitive ion channel FLYC1 using cryo-EM, MD simulations, and electrophysiology, revealing structural features and conformational transitions involved in mechano-gating.

bioRxiv · Jun 30, 2021Biochemistry