Author

S. Elmes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

B. Gini· 1 shared C. Gomez· 1 shared C. M. Blakely· 1 shared D. Barbosa· 1 shared D. L. Kerr· 1 shared L. Tan· 1 shared P. Allegakoen· 1 shared P. Gui· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

B. Gini

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1 paper

Recent·Most cited

CDK4 or CDK6 upregulation induces DNA replication stress and genomic instability to cause EGFR targeted therapy resistance in lung cancer

B. Gini, P. Gui, W. Wu, D. L. Kerr, L. Tan, D. Barbosa, V. Olivas, P. Allegakoen, C. Gomez, P. Halliday, S. Elmes, V. Steri, T. Chakrabarti, T. G. Bivona, C. M. Blakely

This study shows that CDK4/6 upregulation causes DNA replication stress and genomic instability, leading to resistance to EGFR inhibitors in lung cancer, and suggests combining CDK4/6 and EGFR inhibitors as a treatment.

bioRxiv · Mar 12, 2024 · PreprintCancer Biology