A conserved translation factor is required for optimal synthesis of a membrane protein family in mycobacteria
S. Fishbein, I. D. Wolf, C. L. Dulberger, A. Wang, H. Keshishian, L. Wallace, S. A. Carr, T. R. Ioerger, E. J. Rubin, E. H. Rego
This study identifies LepA as a conserved GTPase that enhances the synthesis of mycobacterial porins, affecting drug tolerance and membrane permeability.
bioRxiv · Dec 11, 2019 · PreprintMicrobiology