Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Y. Lee, H. Kim, D. Barker, R. Vijayvargia, R. S. Atwal, H. Specht, H. Keshishian, S. A. Carr, R. Lee, S. Kwak, K.-g. Hyun, J. Loupe, M. E. MacDonald, J.-J. Song, I. Seong
The paper identifies phospho-sites in huntingtin, showing PKA phosphorylation of Ser2550 in the C-HEAT domain accelerates its degradation.
bioRxiv · May 4, 2022 · PreprintBiochemistry
S. Klaeger, A. Apffel, K. R. Clauser, S. Sarkizova, G. Oliveira, S. Rachimi, P. M. Le, A. Tarren, V. Chea, J. G. Abelin, D. A. Braun, P. A. Ott, H. Keshishian, N. Hacohen, D. Keskin, , S. A. Carr
The paper improves HLA-peptidome coverage using optimized liquid and gas phase fractionation methods, enabling detection of more peptides from limited clinical tissue samples.
bioRxiv · May 25, 2021Biochemistry
N. Schmidt, C. A. Lareau, H. Keshishian, R. Melanson, M. Zimmer, L. Kirschner, J. Ade, S. Werner, N. Caliskan, E. S. Lander, J. Vogel, S. A. Carr, J. Bodem, M. Munschauer
This study maps direct RNA-protein interactions of SARS-CoV-2 RNA in infected human cells using RAP-MS, identifying host factors, regulators, and potential drug targets involved in viral replication and host defense.
Nature Microbiology · Dec 21, 2020Peer-reviewedMicrobiology
H. Keshishian, E. R. McDonald, R. Melanson, D. A. Porter, F. Mundth, K. Krug, L. Wallace, D. Forestier, B. Rabasha, S. E. Marlow, J. Jane-Valbuena, E. Todres, H. Specht, J. Golji, E. Kuhn, , S. A. Carr
The paper introduces SigPath, a mass spectrometry assay that quantifies 284 phosphosites across 200 phosphoproteins, revealing new insights into phospho-signaling in cancer models and human tumors.
bioRxiv · Dec 8, 2020Cancer Biology
T. Ouspenskaia, T. Law, K. R. Clauser, S. Klaeger, S. Sarkizova, F. Aguet, B. Li, E. Christian, B. A. Knisbacher, P. M. Le, C. R. Hartigan, H. Keshishian, A. Apffel, G. Oliveira, W. Zhang, , A. Regev
The paper identifies thousands of novel unannotated proteins in cancer that contribute to the MHC I immunopeptidome, expanding potential targets for immunotherapy.
bioRxiv · Feb 12, 2020 · PreprintCancer Biology
S. Fishbein, I. D. Wolf, C. L. Dulberger, A. Wang, H. Keshishian, L. Wallace, S. A. Carr, T. R. Ioerger, E. J. Rubin, E. H. Rego
This study identifies LepA as a conserved GTPase that enhances the synthesis of mycobacterial porins, affecting drug tolerance and membrane permeability.
bioRxiv · Dec 11, 2019 · PreprintMicrobiology