Author

S. Ghiasi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Porse· 1 shared G. A. Rutter· 1 shared J. Nielsen· 1 shared L. Piemonti· 1 shared P. Marchetti· 1 shared T. Mandrup-Poulsen· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

B. Porse

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1 paper

Recent·Most cited

Proinflammatory Cytokines Suppress Nonsense-Mediated RNA Decay to Impair Regulated Transcript Isoform Processing in Pancreatic β-Cells

S. Ghiasi, P. Marchetti, L. Piemonti, J. Nielsen, B. Porse, T. Mandrup-Poulsen, G. A. Rutter

This study shows proinflammatory cytokines suppress NMD activity in β-cells by downregulating UPF3B, leading to increased alternative splicing and ECM-related gene expression, which contributes to β-cell dysfunction.

bioRxiv · Dec 20, 2023Cell Biology