Cell BiologybioRxiv
Centriolar subdistal appendages promote double strand break repair through homologous recombination
G. Rodriguez-Real, A. Dominguez-Calvo, R. Prados-Carvajal…·P. Huertas
This study shows centriolar subdistal appendages and CEP170 promote homologous recombination by enabling DNA end resection, and their loss increases DNA damage sensitivity and correlates with cancer prognosis.
DOI 10.15252/embr.202256724