Author

P. Huertas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:chromatin & epigenetic regulation· 3 Assay:proteomics· 3 Assay:DNA methylation· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Dominguez-Calvo· 3 shared F. R. Balestra· 2 shared A. Bayona-Feliu· 1 shared A. Buff· 1 shared A. J. Lopez-Contreras· 1 shared A. Romero-Franco· 1 shared A. Wals· 1 shared B. Belandia· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCell Biology

A. Dominguez-Calvo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The signaling axis CDK12-BRCA1 mediates dinaciclib associated radiosensitivity through p53-mediated cellular senescence.

N. Garcia-Flores, D. M. Fernandez-Aroca, C. Garnes Garcia, A. Dominguez-Calvo, s. sabater, I. Andres, J. Jimenez Suarez, P. Fernandez-Aroca, F. J. Cimas, G. de Carcer, B. Belandia, I. Palmero, P. Huertas, M. j. Ruiz-Hidalgo, R. Sanchez-Prieto

This paper shows dinaciclib increases radiosensitivity in some cancer cell lines by inhibiting CDK12, reducing BRCA1, and promoting p53-dependent senescence.

bioRxiv · Apr 25, 2024 · PreprintCancer Biology

Circadian regulation of Homologous Recombination by Cryptochrome1-mediated dampening of DNA end resection

A. Romero-Franco, C. Checa-Rodriguez, S. Jimeno, M. Castellano-Pozo, P. Aguilera, H. Miras, A. Wals, S. Jimeno-Gonzalez, A. J. Lopez-Contreras, P. Huertas

The paper shows circadian regulation of DNA resection through CRY1 and CCAR2, impacting cancer progression and radiation response.

bioRxiv · Jan 22, 2023Cell Biology

Centriolar subdistal appendages promote double strand break repair through homologous recombination

G. Rodriguez-Real, A. Dominguez-Calvo, R. Prados-Carvajal, A. Bayona-Feliu, S. Gomes-Pereira, F. R. Balestra, P. Huertas

This study shows centriolar subdistal appendages and CEP170 promote homologous recombination by enabling DNA end resection, and their loss increases DNA damage sensitivity and correlates with cancer prognosis.

bioRxiv · Oct 19, 2022Cell Biology

TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin stability

P. Gönczy, F. R. Balestra, B. Wolf, A. Dominguez-Calvo, A. Buff, T. Averink, M. Lipsanen-Nyman, C. Busso, P. Huertas, R. M. Rios

This study identifies TRIM37's role in preventing centriolar protein assembly by stabilizing Centrobin, which is critical for maintaining genome integrity in Mulibrey nanism.

bioRxiv · Sep 3, 2020Cell Biology