CRISPR targeting of MEIOTIC-TOPOISOMERASE VIB-dCas9 to a recombination hotspot is insufficient to increase crossover frequency in Arabidopsis
N. E. Yelina, S. Gonzalez-Jorge, D. Hirsz, Z. Yang, I. R. Henderson
This study attempts to increase crossover frequency in Arabidopsis by targeting a recombination hotspot with CRISPR-dCas9-MTOPVIB but finds no significant change in crossover frequency or pattern.
bioRxiv · Feb 1, 2021 · PreprintPlant Biology