IL-32 is a metabolic regulator promoting survival and proliferation of malignant plasma cells
K. R. Aass, R. Mjelle, M. H. Kastnes, S. S. Tryggestad, L. M. van den Brink, M. Westhrin, M. Zahoor, S. H. Moen, G. Buene, K. Misund, A.-M. Sponaas, Q. Ma, A. Sundan, R. W. Groen, T. S. Slordahl, , T. Standal
This study shows IL-32 promotes survival and proliferation of malignant plasma cells by enhancing mitochondrial oxidative phosphorylation and altering metabolic pathways.
bioRxiv · Feb 22, 2021 · PreprintCancer Biology