Author

R. W. Groen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Sundan· 2 shared G. Buene· 2 shared M. Westhrin· 2 shared M. Zahoor· 2 shared S. H. Moen· 2 shared T. Standal· 2 shared A. M. Sponaas· 1 shared A. Martens· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

A. Sundan

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Author profile →

3 papers

Recent·Most cited

Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable Interaction with CTBP2

D. Pastoors, M. Havermans, R. Mulet-Lazaro, D. Brian, W. Noort, J. Grasel, R. Hoogenboezem, L. Smeenk, J. A. Demmers, T. Enver, R. W. Groen, E. Bindels, R. Delwel

This study identifies EVI1's interaction with CTBP1/CTBP2 as critical for AML and shows that inhibiting this interaction can block leukemic growth.

bioRxiv · Jul 11, 2023Cancer Biology

IL-32 is a metabolic regulator promoting survival and proliferation of malignant plasma cells

K. R. Aass, R. Mjelle, M. H. Kastnes, S. S. Tryggestad, L. M. van den Brink, M. Westhrin, M. Zahoor, S. H. Moen, G. Buene, K. Misund, A.-M. Sponaas, Q. Ma, A. Sundan, R. W. Groen, T. S. Slordahl, , T. Standal

This study shows IL-32 promotes survival and proliferation of malignant plasma cells by enhancing mitochondrial oxidative phosphorylation and altering metabolic pathways.

bioRxiv · Feb 22, 2021 · PreprintCancer Biology

Bone morphogenetic protein 4 gene therapy in mice inhibits myeloma tumor growth, but has a negative impact on bone

M. Westhrin, T. Holien, M. Zahoor, S. H. Moen, G. Buene, B. Stordal, H. Hella, H. Yuan, J. D. de Bruijn, A. Martens, R. W. Groen, F. Bosch, U. Smith, A. M. Sponaas, A. Sundan, T. Standal

This study shows that BMP4 gene therapy reduces myeloma tumor growth in mice but also decreases trabecular bone volume.

bioRxiv · Mar 13, 2019Cancer Biology