Author

S. H. Smits

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Organism:fungi (other)· 1 Organism:human· 1

Frequent Co-Authors

L. Schmitt· 4 shared J. Reiners· 3 shared E. Hachani· 2 shared K. Muentjes· 2 shared A. Hamacher· 1 shared A. Hoeppner· 1 shared A. Kedrov· 1 shared A. Papadopoulos· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersBiochemistry

L. Schmitt

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Deciphering the RNA-binding protein network during endosomal mRNA transport

S. K. Devan, S. Shanmugasundaram, K. Muentjes, S. H. Smits, F. Altegoer, M. Feldbrugge

This study identifies structural features of the MLLE domain in Rrm4 and reveals its role in recognizing short linear motifs for mRNA transport during endosomal trafficking.

bioRxiv · Mar 22, 2024Microbiology

Heterologously secreted MbxA from Moraxella bovis induces a membrane blebbing response of the human host cell

I. N. Erenburg, S. Haensch, F. M. Chacko, A. Hamacher, S. Wintgens, F. Stuhldreier, G. Poschmann, O. Spitz, K. Stuehler, S. Wesselborg, J. Hegemann, S. H. Smits, S. Weidtkamp-Peters, L. Schmitt

The paper shows that MbxA from Moraxella bovis, secreted via an E. coli system, induces membrane blebbing and cell death in human cells.

bioRxiv · May 2, 2022Biochemistry

The periplasmic chaperone Skp prevents misfolding of the secretory lipase A from Pseudomonas aeruginosa

A. Papadopoulos, M. Busch, J. Reiners, E. Hachani, M. Baeumers, L. Schmitt, K.-E. Jaeger, F. Kovacic, S. H. Smits, A. Kedrov

This study shows that Skp prevents misfolding of lipase A in Pseudomonas aeruginosa and facilitates its activation by LipH, with two binding modes identified.

bioRxiv · Mar 1, 2022Biochemistry

A MademoiseLLE domain binding platform links the key RNA transporter to endosomes

S.-K. Devan, S. Schott-Verdugo, K. Muentjes, L. Bismar, J. Reiners, E. Hachani, L. Schmitt, A. Hoeppner, S. H. Smits, H. Gohlke, M. Feldbruegge

The paper identifies MLLE domains in Rrm4 as essential for endosomal attachment, revealing a hierarchical binding platform for mRNA transport.

bioRxiv · Oct 25, 2021Microbiology

Mechanism of the secretion of the lanthipeptide nisin

M. Lagedroste, J. Reiners, S. H. Smits, L. Schmitt

The paper investigates the secretion mechanism of nisin, showing that NisC modulates secretion rates while NisB's presence affects it, and that NisT's activity is influenced by maturation enzymes.

bioRxiv · Nov 12, 2019 · PreprintBiochemistry