Mmp14 is required for matrisome homeostasis and circadian rhythm in fibroblasts
C.-Y. C. Yeung, R. Garva, A. Pickard, Y. Lu, V. Mallikarjun, J. Swift, S. H. Taylor, J. Rai, D. R. Eyre, M. Chaturvedi, Y. Itoh, Q.-J. Meng, C. Mauch, P. Zigrino, K. E. Kadler
This study shows that Mmp14 regulates circadian rhythms and matrisome homeostasis in tendon fibroblasts by controlling collagen fibril synthesis and crosslinking.
bioRxiv · Apr 1, 2022Cell Biology