Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
C. F. Goncalves, M. Dudek, D. R. Pathiranage, A. Paszek, Z. El-Houni, S. Li, G. Tawy, L. Biant, J. A. Hoyland, Q.-J. Meng
This study shows that heat pulses can restore circadian rhythms in cartilage by modulating heat shock proteins and circadian clock genes.
bioRxiv · Jan 26, 2024Cell Biology
M. Dudek, H. Morris, N. Rogers, D. R. Pathiranage, D. Chan, K. E. Kadler, J. A. Hoyland, Q.-J. Meng
This study shows that BMAL1, a circadian clock factor, regulates ECM homeostasis and cell fate in the intervertebral disc, with its loss causing ECM dysregulation and osteogenic differentiation.
bioRxiv · Feb 12, 2023Physiology
C.-Y. C. Yeung, R. Garva, A. Pickard, Y. Lu, V. Mallikarjun, J. Swift, S. H. Taylor, J. Rai, D. R. Eyre, M. Chaturvedi, Y. Itoh, Q.-J. Meng, C. Mauch, P. Zigrino, K. E. Kadler
This study shows that Mmp14 regulates circadian rhythms and matrisome homeostasis in tendon fibroblasts by controlling collagen fibril synthesis and crosslinking.
bioRxiv · Apr 1, 2022Cell Biology
M. Dudek, D. Pathiranage, C. F. Goncalves, C. Lawless, D. Wang, Z. Luo, L. Yang, F. Guilak, J. A. Hoyland, Q.-J. Meng
The paper shows mechanical loading and hyperosmolarity reset circadian clocks in skeletal tissues via the mTORC2-AKT-GSK3β pathway, inducing rhythmic gene expression.
bioRxiv · Oct 1, 2021Physiology
M. Dudek, C. Angelucci, J. P. Ruckshanthi, P. Wang, V. Mallikarjun, C. Lawless, K. E. Kadler, J. A. Hoyland, S. R. Lamande, J. F. Bateman, Q.-J. Meng
This study uses circadian time-series proteomics to identify daily protein abundance changes in mouse articular cartilage, revealing rhythmic proteins and their dysregulation in osteoarthritis and aging.
bioRxiv · May 31, 2019Physiology