A family of novel immune systems targets early infection of nucleus-forming jumbo phages
Y. Li, J. Guan, S. Hareendranath, E. Crawford, D. A. Agard, K. S. Makarova, E. V. Koonin, J. Bondy-Denomy
This study identifies a novel immune system, Juk, in Pseudomonas aeruginosa that targets jumbo phages by inhibiting early phage transcription, DNA replication, and nucleus assembly.
bioRxiv · Sep 17, 2022 · PreprintMicrobiology