Endothelial-specific reduction in Arf6 impairs insulin-stimulated vasodilation and skeletal muscle blood flow resulting in systemic insulin resistance
M. T. Islam, J. Cai, S. Allen, R. C. Bramwell, J. Mitton, A. G. Horn, W. Zhu, A. J. Donato, W. L. Holland, L. A. Lesniewski, D. G. Moreno, S. I. Bloom
This study shows that reducing Arf6 in endothelial cells impairs insulin-stimulated vasodilation and causes systemic insulin resistance.
bioRxiv · May 2, 2023Physiology