S. I. Dreher

Mesenchymal stromal cell chondrogenesis under ALK1/2/3-specific BMP inhibition: A revision of the prohypertrophic signalling network concept

This study investigates the role of ALK1/2/3 inhibition in mesenchymal stromal cell chondrogenesis, finding that BMP-ALK1/2/3 signaling is not a driver of hypertrophy and that PTHrP/hedgehog and WNT signaling are more critical in hypertrophic differentiation.

Engineering of human myotubes toward a mature metabolic and contractile phenotype

This paper shows that adding IGF1 to human myoblast cultures improves their contractility and metabolic profile, making them more like mature skeletal muscle.