Author

S. Ilangumaran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

S. Ramanathan· 4 shared A. Ghosh· 2 shared M. A. Santharam· 2 shared A. Cantin· 1 shared A. J. I. Quenum· 1 shared A. J. Quenum· 1 shared A. Menendez· 1 shared A. Piche· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersImmunology

S. Ramanathan

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Author profile →

4 papers

Recent·Most cited

SARS-CoV-2 spike antigen-specific B cell and antibody responses in pre-vaccination period COVID-19 convalescent males and females with or without post-covid condition

M.-A. Limoges, A. J. I. Quenum, M. M. H. Chowdhury, F. Rexhepi, M. Namvarpour, S. A. Akbari, C. Rioux-Perreault, M. Nandi, J.-F. Lucier, S. Lemaire-Paquette, L. Premkumar, Y. Durocher, A. Cantin, S. Levesque, A. Menendez, , S. Ramanathan

This study examines B cell and antibody responses to SARS-CoV-2 antigens in individuals with and without post-COVID condition (PCC), finding sex-related differences in antibody responses to the spike protein.

bioRxiv · Apr 13, 2023 · PreprintImmunology

SOCS3-mediated activation of p53-p21-NRF2 axis and cellular adaptation to oxidative stress in SOCS1-deficient hepatocellular carcinoma

M. M. Khan, N. Boufaied, M. Yeganeh, A. Ghosh, R. Kandhi, R. Bagheri, S. Petkiewicz, A. Sharma, A. Yoshimura, G. Ferbeyre, D. P. Labbe, S. Ramanathan, S. Ilangumaran

The paper shows that SOCS1 deficiency leads to increased SOCS3 expression, which activates the p53-p21-NRF2 axis, reducing oxidative stress and HCC progression.

bioRxiv · Oct 21, 2021 · PreprintCancer Biology

Cytokine priming of naive CD8+ T lymphocytes modulates chromatin accessibility that partially overlaps with changes induced by antigen simulation

A. J. Quenum, M. Cloutier, M. A. Santharam, M. Mayhue, S. Ramanathan, S. Ilangumaran

This study shows cytokine priming of naive CD8+ T cells changes chromatin accessibility, with some overlaps seen with antigen stimulation, suggesting a poised state for enhanced TCR responsiveness.

bioRxiv · Aug 11, 2020 · PreprintImmunology

Prognostic significance of SOCS1 and SOCS3 tumor suppressors in hepatocellular carcinoma and its correlation to key oncogenic signaling pathways

M. G. M. Khan, A. Ghosh, B. Variya, M. A. Santharam, A. U. Ihsan, S. Ramanathan, S. Ilangumaran

The paper evaluates SOCS1 and SOCS3 expression in hepatocellular carcinoma and their correlation with oncogenic pathways, finding some genes predict prognosis when combined with SOCS1/SOC3 levels.

bioRxiv · Feb 21, 2020Cancer Biology