Author

G. Ferbeyre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Schmitzer· 2 shared A. Dore· 1 shared A. Fernandez· 1 shared A. Ghosh· 1 shared A. Hebert· 1 shared A. Sharma· 1 shared A. Yoshimura· 1 shared D. P. Labbe· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. Schmitzer

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Author profile →

4 papers

Recent·Most cited

Biguanide-PROTACs: Modulating Mitochondrial Proteins in Pancreatic Cancer Cells

J. Vatte, V. Bourdeau, G. Ferbeyre, A. Schmitzer

This study synthesizes Biguanide-PROTACs and evaluates their activity on pancreatic cancer cells, finding structure-permeability-activity relationships and some AMPK activation.

bioRxiv · Mar 17, 2024 · PreprintCancer Biology

SOCS3-mediated activation of p53-p21-NRF2 axis and cellular adaptation to oxidative stress in SOCS1-deficient hepatocellular carcinoma

M. M. Khan, N. Boufaied, M. Yeganeh, A. Ghosh, R. Kandhi, R. Bagheri, S. Petkiewicz, A. Sharma, A. Yoshimura, G. Ferbeyre, D. P. Labbe, S. Ramanathan, S. Ilangumaran

The paper shows that SOCS1 deficiency leads to increased SOCS3 expression, which activates the p53-p21-NRF2 axis, reducing oxidative stress and HCC progression.

bioRxiv · Oct 21, 2021 · PreprintCancer Biology

Phenylethynylbenzyl-Modified Biguanides Inhibit Pancreatic Cancer Tumor Growth

A. Hebert, M. Parisotto, M.-C. Rowell, A. Dore, A. Fernandez, G. Lefrancois, P. Kalegari, G. Ferbeyre, A. Schmitzer

The paper designs and tests phenylethynylbenzyl-modified biguanides, showing they inhibit pancreatic cancer growth more effectively than existing biguanides.

bioRxiv · Oct 7, 2019Cancer Biology

Senescence associated protein degradation

G. Ferbeyre

The paper identifies senescence-associated protein degradation via ERK/MAP kinase pathway activation in senescent cells and discusses its role in organismal aging.

bioRxiv · Jan 15, 2017Cell Biology