Author

S. J. Fuller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

A. Clerk· 2 shared H. O. Alharbi· 2 shared J. J. Cull· 2 shared M. A. Hardyman· 2 shared P. E. Glennon· 2 shared P. H. Sugden· 2 shared S. T. Cooper· 2 shared T. Markou· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

A. Clerk

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural insights into the heterotrimeric alternatively spliced P2X7 receptorsCondensed title: Structures of heterotrimeric P2X7 receptors

S. K. F. De Salis, J. Z. Chen, K. K. Skarratt, S. J. Fuller, T. Balle

This study uses AlphaFold2-Multimer to generate structures of heterotrimeric P2X7 receptors, revealing structural insights and potential functional differences in splice variants.

bioRxiv · May 30, 2023 · PreprintBiophysics

Cardiomyocyte BRAF is a key signalling intermediate in cardiac hypertrophy in mice

H. O. Alharbi, M. A. Hardyman, J. J. Cull, T. Markou, S. T. Cooper, P. E. Glennon, S. J. Fuller, P. H. Sugden, A. Clerk

This study shows that BRAF in cardiomyocytes is essential for male mouse cardiac hypertrophy and fibrosis in hypertension but has opposing effects in physiological hypertrophy, with sex-specific differences.

bioRxiv · Sep 7, 2022Physiology

Cardiomyocyte BRAF and type 1 RAF inhibitors promote cardiomyocyte and cardiac hypertrophy in mice in vivo

A. Clerk, D. N. Meijles, M. A. Hardyman, S. J. Fuller, S. P. Chothani, J. J. Cull, S. T. Cooper, H. O. Alharbi, K. Vanezis, L. E. Felkin, T. Markou, S. J. Leonard, S. W. Shaw, O. J. Rackham, S. A. Cook, , P. H. Sugden

This study shows that BRAF activation induces cardiac hypertrophy in mice, and Type 1 RAF inhibitors paradoxically promote hypertrophy by increasing ERK1/2 phosphorylation.

bioRxiv · Aug 14, 2021Biochemistry