Author

S. L. Yilmaz

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Biochemistry· 1

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Organism:C. elegans· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. J. M. Walhout· 1 shared B. W. Fox· 1 shared F. C. Schroeder· 1 shared G. E. Giese· 1 shared H. Zhang· 1 shared O. Ponomarova· 1 shared S. Nanda· 1 shared T. B. Leland· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. J. M. Walhout

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1 paper

Recent·Most cited

A D-2-Hydroxyglutarate dehydrogenase mutant reveals a critical role for ketone body metabolism in Caenorhabditis elegans development

O. Ponomarova, H. Zhang, X. Li, S. Nanda, T. B. Leland, B. W. Fox, G. E. Giese, F. C. Schroeder, S. L. Yilmaz, A. J. M. Walhout

This study shows that in C. elegans, D-2HG is produced via the propionate shunt and that loss of dhgd-1 causes embryonic lethality by disrupting ketone body metabolism, which can be rescued by vitamin B12 or 3-hydroxybutyrate.

bioRxiv · May 16, 2022Biochemistry