Author

B. W. Fox

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

F. C. Schroeder· 4 shared A. B. Artyukhin· 1 shared A. J. M. Walhout· 1 shared A. R. Kolodziej· 1 shared D. C. F. Palomino· 1 shared D. Lee· 1 shared E. C. Andersen· 1 shared E. Gelsleichter· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersBiochemistry

F. C. Schroeder

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Author profile →

4 papers

Recent·Most cited

ATP-release pannexin channels are gated by lysophospholipids

E. Henze, R. N. Burkhardt, B. W. Fox, T. J. Schwertfeger, E. Gelsleichter, K. Michalski, L. Kramer, M. Lenfest, J. M. Boesch, H. Lin, F. C. Schroeder, T. Kawate

The paper identifies lysophospholipids as activators of pannexin channels, showing they trigger ATP and other metabolite release, and activate inflammasomes in human monocytes.

bioRxiv · Oct 23, 2023Biophysics

Natural genetic variation in the pheromone production of C. elegans

D. Lee, B. W. Fox, D. C. F. Palomino, O. Panda, F. J. Tenjo, K. S. Evans, L. Stevens, E. Koury, P. R. Rodrigues, A. R. Kolodziej, F. C. Schroeder, E. C. Andersen

The paper identifies genetic factors influencing ascaroside pheromone variation in C. elegans using metabolomic and genomic analysis.

bioRxiv · Nov 23, 2022Evolutionary Biology

A D-2-Hydroxyglutarate dehydrogenase mutant reveals a critical role for ketone body metabolism in Caenorhabditis elegans development

O. Ponomarova, H. Zhang, X. Li, S. Nanda, T. B. Leland, B. W. Fox, G. E. Giese, F. C. Schroeder, S. L. Yilmaz, A. J. M. Walhout

This study shows that in C. elegans, D-2HG is produced via the propionate shunt and that loss of dhgd-1 causes embryonic lethality by disrupting ketone body metabolism, which can be rescued by vitamin B12 or 3-hydroxybutyrate.

bioRxiv · May 16, 2022Biochemistry

Comparative metabolomics with Metaboseek reveals functions of a conserved fat metabolism pathway in C. elegans

M. J. Helf, B. W. Fox, A. B. Artyukhin, Y. K. Zhang, F. C. Schroeder

The paper introduces Metaboseek, a platform for untargeted metabolomics, and uses it to discover functions of a conserved fat metabolism pathway in C. elegans.

bioRxiv · Sep 7, 2021Biochemistry