Author

S. Lakshmikanthan

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

G. P. Sharma· 1 shared G. Xin· 1 shared M. Chrzanowska· 1 shared R. Burns· 1 shared R. Kosuru· 1 shared S. Zheng· 1 shared W. Cui· 1 shared Y. Chen· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

G. P. Sharma

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1 paper

Recent·Most cited

Endothelial Rap1B mediates T-cell exclusion to promote tumor growth -a novel mechanism underlying vascular immunosuppression

G. P. Sharma, R. Kosuru, S. Lakshmikanthan, S. Zheng, Y. Chen, R. Burns, G. Xin, W. Cui, M. Chrzanowska

This study identifies EC Rap1B as a key mediator of vascular immunosuppression by promoting T-cell exclusion and tumor growth through regulation of CAMs and NFκB signaling.

bioRxiv · Nov 3, 2021Cancer Biology