Author

S. Lekkala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

A. J. H. Tay· 1 shared A. Sekar· 1 shared B. Liu· 1 shared C. Xie· 1 shared D. Kannambadi· 1 shared E. M. Schwarz· 1 shared E. Oral· 1 shared F. Malick· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. J. H. Tay

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Investigating the translational value of Periprosthetic Joint Infection (PJI) models to determine the risk and severity of Staphylococcal biofilms.

A. Sekar, Y. Fan, P. Tierney, M. McCanne, P. Jones, F. Malick, D. Kannambadi, K. K. Wannomae, N. Inverardi, J. Yuh, S. Lekkala, O. K. Muratoglu, E. Oral

This study evaluates preclinical models to assess the risk and severity of Staphylococcal biofilms in periprosthetic joint infections and their antibiotic susceptibility.

bioRxiv · Apr 29, 2024Microbiology

A semi-automated cell tracking protocol for quantitative analyses of neutrophil swarming to sterile and S. aureus contaminated bone implants in a mouse femur model

S. Lekkala, Y. Ren, J. Weeks, K. Lee, A. J. H. Tay, B. Liu, T. Xue, J. Rainbolt, C. Xie, E. M. Schwarz, S.-C. A. Yeh

This paper develops a semi-automated cell tracking protocol to quantify neutrophil swarming in a mouse femur model with and without S. aureus infection, showing increased speed, displacement, and directionality in infected mice.

bioRxiv · Dec 7, 2023 · PreprintImmunology