Author

S. M. Burnard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. R. Bond· 2 shared H. J. Lee· 2 shared S. Humphries· 2 shared A. K. Enjeti· 1 shared A. Mannan· 1 shared B. M. Harvey· 1 shared C. de Bock· 1 shared C. Lawlor-O'Neill· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

D. R. Bond

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Author profile →

2 papers

Recent·Most cited

Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for AML cell self-renewal.

D. R. Bond, S. M. Burnard, K. Uddipto, K. V. Hunt, B. M. Harvey, L. Steffens Reinhardt, C. Lawlor-O'Neill, E. A. Roper, S. Humphries, H. C. Murray, A. Mannan, M. D. Dun, C. de Bock, N. A. Bowden, A. K. Enjeti, , H. J. Lee

This study shows that hypomethylating agents induce epigenetic and transcriptional heterogeneity in AML cells, with some cells retaining methylation and showing increased self-renewal, and identifies statins as a potential co-treatment to enhance HMA efficacy.

bioRxiv · Jan 30, 2024Cancer Biology

Hypoxia alters the effects of hypomethylating agents in acute myeloid leukaemia cells.

S. Humphries, S. M. Burnard, S. Keely, D. R. Bond, H. J. Lee

This study shows hypoxia reduces the effectiveness of hypomethylating agents in AML cells by altering DNA methylation and antigen presentation pathways.

bioRxiv · Dec 7, 2023Cancer Biology