D. R. Bond

Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for AML cell self-renewal.

This study shows that hypomethylating agents induce epigenetic and transcriptional heterogeneity in AML cells, with some cells retaining methylation and showing increased self-renewal, and identifies statins as a potential co-treatment to enhance HMA efficacy.

Hypoxia alters the effects of hypomethylating agents in acute myeloid leukaemia cells.

This study shows hypoxia reduces the effectiveness of hypomethylating agents in AML cells by altering DNA methylation and antigen presentation pathways.

Single amino acid residues control potential-dependent inactivation of an inner membrane bc-cytochrome

The paper identifies single amino acid mutations in CbcL that prevent redox potential-dependent inactivation, allowing growth at higher potentials.

Lack of specificity in Geobacter periplasmic electron transfer

This study shows that multiple triheme periplasmic cytochromes in Geobacter sulfurreducens are promiscuous in electron transfer, supporting metal reduction but not electrode respiration.

Environmental predictors of electroactive bacterioplankton in small boreal lakes.

The paper identifies environmental predictors of electroactive bacterioplankton in small boreal lakes by analyzing EET genes and their correlation with DOM.

Geobacter sulfurreducens inner membrane cytochrome CbcBA controls electron transfer and growth yield near the energetic limit of respiration.

This paper identifies CbcBA as an essential bc-type cytochrome in Geobacter sulfurreducens that regulates electron transfer and growth yield under low redox potential conditions.

Identification of different putative outer membrane electron conduits necessary for Fe(III) citrate, Fe(III) oxide, Mn(IV) oxide, or electrode reduction by Geobacter sulfurreducens

This study identifies different gene clusters in Geobacter sulfurreducens essential for reducing various electron acceptors, showing gene-specific requirements for metal oxides and electrodes.

Geobacter sulfurreducens extracellular multiheme cytochrome PgcA facilitates respiration to Fe(III) oxides but not electrodes

This study shows that PgcA in Geobacter sulfurreducens is essential for electron transfer to Fe(III) oxides but not electrodes.

Genome scale mutational analysis of Geobacter sulfurreducens reveals distinct molecular mechanisms for respiration of poised electrodes vs. Fe(III) oxides

This study uses Tn-Seq to identify genes essential for Geobacter sulfurreducens growth with electrodes versus Fe(III) oxides, revealing distinct molecular mechanisms for electron transfer.