Author

S. M. Coldewey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:rat· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Thiemermann· 2 shared E. Aimaretti· 2 shared G. Ferreira Alves· 2 shared M. Collino· 2 shared N. M. Patel· 2 shared A. Kolte· 1 shared C. L. Sprung· 1 shared D. Collotta· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

C. Thiemermann

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inhibition of the JAK/STAT pathway with baricitinib reduces the multiple organ dysfunction caused by hemorrhagic shock in rats

N. M. Patel, D. Collotta, E. Aimaretti, G. Ferreira Alves, S. Kröller, S. M. Coldewey, M. Collino, C. Thiemermann

This study shows that baricitinib reduces multiple organ dysfunction in hemorrhagic shock rats by inhibiting JAK/STAT, NF-κB, and NLRP3 pathways.

bioRxiv · Jan 13, 2022Pharmacology & Toxicology

Inhibition of Bruton's tyrosine kinase activity attenuates trauma-induced multiple organ dysfunction in rats

N. M. Patel, F. R. Oliveira, H. Pillmann Ramos, E. Aimaretti, G. Ferreira Alves, S. M. Coldewey, M. Collino, R. Sordi, C. Thiemermann

This study shows that BTK inhibitors reduce trauma-induced multiple organ dysfunction in rats by inhibiting BTK, NF-κB, and NLRP3 activation.

bioRxiv · Sep 23, 2021Pharmacology & Toxicology

Use of IFNγ/IL10 ratio for stratification of hydrocortisone therapy in patients with septic shock

R. Koenig, A. Kolte, O. Ahlers, M. Oswald, D. Roell, G. Dimopoulos, I. Tsangaris, E. Antoniadou, H. Bogatsch, M. Loeffler, C. L. Sprung, M. Singer, F. Brunkhorst, M. Oppert, H. Gerlach, , M. Bauer

This paper identifies the IFNγ/IL10 ratio as a biomarker to guide hydrocortisone therapy in septic shock, showing improved survival when treatment aligns with the ratio's prediction.

bioRxiv · Dec 21, 2018Immunology